Which medication is commonly used as a prophylactic treatment for migraines?

Topiramate is commonly used as a prophylactic treatment for migraines due to its ability to stabilize neuronal activity and reduce the frequency of migraine attacks. It is classified as an anticonvulsant, but its properties also make it effective in migraine prevention. The medication works by various mechanisms, such as inhibiting excitatory neurotransmitters and enhancing inhibitory neurotransmitters, which can help to prevent the initiation of migraine attacks.

While other medications like amitriptyline can also be effective for migraine prophylaxis, topiramate is specifically recommended in many clinical guidelines due to its efficacy demonstrated in various studies. It is often favored because of its favorable side effect profile in comparison to some other prophylactic treatments.