What condition can improve with the use of combined oral contraceptives?

The use of combined oral contraceptives (COCs) is well-established in the management of various conditions, and one of the notable improvements seen with their use is in acne vulgaris. COCs work by regulating hormonal fluctuations that can lead to increased androgen levels, which are responsible for stimulating sebaceous gland activity and promoting acne formation. By lowering circulating levels of androgens, combined oral contraceptives can reduce acne lesions and improve overall skin appearance in affected individuals.

In the context of cycle control, breast tenderness, and menorrhagia, while COCs can influence these conditions, their primary and most consistent efficacy is observed in the treatment of acne vulgaris. For instance, COCs can indeed help manage cycle irregularities and reduce heavy menstrual bleeding (menorrhagia) by stabilizing hormonal levels. Similarly, breast tenderness may improve as a side effect of hormonal regulation. However, these effects can vary greatly among individuals and are not as specific or reliable as the impact of COCs on acne treatment, which has been documented in numerous studies and is widely recognized in clinical practice.