The growth of benign uterine tumors is influenced predominantly by which hormones?

Benign uterine tumors, commonly referred to as fibroids or leiomyomas, are primarily influenced by the hormones estrogen and progesterone. These hormones play a pivotal role in the reproductive cycle and have a significant impact on the growth and development of uterine tissue.

Estrogen promotes the proliferation of uterine cells, and its levels naturally increase during the reproductive years. In response to estrogen, the uterine lining thickens in preparation for potential pregnancy. This hormonal influence is crucial for the growth of benign tumors, as these tumors have been shown to have estrogen receptors, indicating a direct effect of estrogen stimulation on their growth.

Progesterone, on the other hand, contributes to the regulation of the menstrual cycle and may also influence fibroid growth. Progesterone works alongside estrogen, playing a role in maintaining the uterine lining during the second half of the menstrual cycle. It can help to modulate the effects of estrogen on the tissue and can also be involved in the tumor growth dynamics.

In contrast, the hormones listed in the other options typically have different roles in the body. Luteinizing hormone and gonadotropin-stimulating hormone mainly control ovulation and the menstrual cycle rather than directly influencing the growth of uterine tumors. Cort